B-RAF (fosfo Thr599) Antilichaam

Involved in the transduction of mitogenic signals from the cell membrane to the nucleus. May play a role in the postsynaptic responses of hippocampal neuron.

673

P15056

NP_004324.2

Human, Mouse, Rat

B-RAF (phospho Thr599) antibody was raised against a peptide sequence around phosphorylation site of threonine 599 (L-A-T (p) -V-K) derived from Human B-RAF.

Unconjugated

Primary Antibodies

Phospho-Specific

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Phospho-Specific

Blue Ice

Store antibody at -20˚ C for up to one year.

84 kDa

IgG

The antibody detects endogenous levels of B-Raf only when phosphorylated at threonine 598.

BRAF

V-raf murine sarcoma viral oncogene homolog B1

Homo sapiens

Armelle Calipel, J. Biol. Chem., Oct 2003; 278: 42409 - 42418.

Tara J. Dillon, J. Biol. Chem., Sep 2003; 278: 35940 - 35949.

R K Jaiswal, Mol. Cell. Biol., Oct 1994; 14: 6944 - 6953.

Laura L. Dugan, J. Biol. Chem., Sep 1999; 274: 25842.

B-RAF, RAFB1, RMIL, BRAF1, c-RMIL

IHC

50403720

Liquid