B7-H4-eiwit, humaan, recombinant (hFc & Avi), biotinyleerd
Gecertificeerd

B7-H4-eiwit, humaan, recombinant (hFc & Avi), biotinyleerd

Catalog #: TMPJ-00176-01
Maat: 5 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Bioactivity

B7 Homolog 4 (B7-H4) is glycosylated member of the B7 family of immune costimulatory proteins. Mature human B7-H4 consists of a 235 amino acid (aa) extracellular domain (ECD) with two Ig-like V-type domains, a 21 aa transmembrane segment, and a 2 aa cytoplasmic tail. It is widely expressed, including in kidney, liver, lung, pancreas, placenta, prostate, spleen, testis and thymus. B7-H4 negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor-associated antigen-specific T-cell immunity. It also involved in promoting epithelial cell transformation.

Shipping Conditions

Ice Packs

Storage Temperature

-20°C

Beschrijving

B7-H4-eiwit, humaan, recombinant (hFc & Avi), biotinyleerd Beschikbaar in 5 µg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamB7-H4-eiwit, humaan, recombinant (hFc & Avi), biotinyleerd
Categorie
Beschikbare grootte5 µg
CatalogusnummerTMPJ-00176-01