BABAM2 Antilichaam - C-terminaal gebied : HRP (ARP62254 P050-HRP)

BRISC and BRCA1 A complex member 2

BRE, BRCC4, BRCC45

9577

Q9NXR7

NP_954664

Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish

This gene encodes an anti-apoptotic, death receptor-associated protein that interacts with tumor necrosis factor-receptor-1. The encoded protein acts as an adapter in several protein complexes, including the BRCA1-A complex and the BRISC complex. The BRCA1-A complex possesses ubiquitinase activity and targets sites of double strand DNA breaks, while the BRISC complex exhibits deubiquitinase activity and is involved in mitotic spindle assembly. This gene is upregulated in several types of cancer.

FAM175B; UBC; BABAM1; AKAP2; TFG; OPTN; HNRNPA2B1; SUMO2; PAXIP1; MDC1; BRCA1; GRB2; UBD; GFI1B; UIMC1; BRCC3; FAM175A; NCOA3; COPS5; SUMO1; TNFRSF1A; FAS; MMS19; UGGT2; TMX3; DHRS7B; FKBP8; TTC28; ATG2A; SLC25A13; LRPPRC; USP7; SSR3; SHMT2; RPN2; PHB; UB

HRP: Horseradish Peroxidase

Polyclonal Antibody

WB, IHC

Affinity Purified

BRE is strongly supported by BioGPS gene expression data to be expressed in A549

0.5 mg/ml

Cow: 100%; Dog: 100%; Guinea Pig: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Rabbit: 100%; Rat: 100%; Zebrafish: 100%

Liquid. Purified antibody is supplied in high phosphate PBS, 100 mm phosphate, 150 mM NaCl, pH 7.6.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

43kDa

Wet Ice

383

BABAM2

BABAM2

Rabbit

BRISC and BRCA1-A complex member 2

NM_199194

YHFTNSGQLYSQAQKNYPYSPRWDGNEMAKRAKAYFKTFVPQFQEAAFAN

BRE