BACE1 Antilichaam [3C1C3]

Cerebral deposition of amyloid beta peptide is an early and critical feature of Alzheimer's disease. Amyloid beta peptide is generated by proteolytic cleavage of amyloid precursor protein (APP) by two proteases, one of which is the protein encoded by this gene. The encoded protein, a member of the peptidase A1 protein family, is a type I integral membrane glycoprotein and aspartic protease that is found mainly in the Golgi. Multiple transcript variants encoding different isoforms have been described for this gene.

23621

P56817

Human, Mouse, Rat

Rurified recombinant fragment of human BACE1 (AA: 112-324) expressed in E. Coli.

3C1C3

Unconjugated

Primary Antibodies

Neuroscience

Batch dependent

Purified antibody in PBS with 0.05% sodium azide.

None

Blue Ice

BACE monoclonal antibody can be stored at -20˚ C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG1

BACE1

Beta-secretase 1

Homo sapiens

J Neurochem. 2012 Jan;120 Suppl 1:62-70.

Eur J Neurosci. 2010 Oct;32 (7) :1223-38.

BACE Antibody: ASP2, BACE, HSPC104, KIAA1149, Beta-secretase 1, Aspartyl protease 2, ASP2

ELISA, WB, ICC, Flow