BACH1 Antilichaam - C-terminalgebied: Biotine (ARP38012_T100-Biotine)

BTB and CNC homology 1, basic leucine zipper transcription factor 1

BACH-1, BTBD24

571

O14867

NP_001177

Human

The immunogen is a synthetic peptide directed towards the C terminal region of human BACH1

BACH1 is a transcription factor that belongs to the cap'n'collar type of basic region leucine zipper factor family (CNC-bZip) . The encoded protein contains broad complex, tramtrack, bric-a-brac/poxvirus and zinc finger (BTB/POZ) domains, which is atypical of CNC-bZip family members. These BTB/POZ domains facilitate protein-protein interactions and formation of homo- and/or hetero-oligomers. When this encoded protein forms a heterodimer with MafK, it functions as a repressor of Maf recognition element (MARE) and transcription is repressed. Multiple alternatively spliced transcript variants have been identified for this gene. Some exons of this gene overlap with some exons from the C21orf41 gene, which is transcribed in an opposite orientation to this gene but does not seem to encode a protein.

NFE2L2; BRCA1; SMAD3; FBXL17; NLK; UBC; MAFF; MAFB; MAFG; DDIT3; ATF2; CSNK1A1; ANAPC5; PALB2; TOPBP1; NBN; MRE11A; MLH1; BARD1; Bach1; HMMR; BRCA2; BRCC3; XPO1; NCOR1; MAFK; TP53; HDAC1; PATZ1; RBCK1; PARK2

Biotin

Polyclonal Antibody

WB

0.5 mg/ml

Human: 100%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

82kDa

Litman, R., et al., (2005) Cancer Cell 8 (3), 255-265

Wet Ice

736

BACH1

BACH1

Rabbit

Transcription regulator protein BACH1

NM_001186

PPCARGNSEPGYARGQESQQMSTATSEQAGPAEQCRQSGGISDFCQQMTD