BAIAP2 Mouse Monoclonal Antibody [Kloon ID: LBI8G8]

The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1) -binding protein. This adaptor protein links membrane bound G-proteins to cytoplasmic effector proteins. This protein functions as an insulin receptor tyrosine kinase substrate and suggests a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is associated with the formation of stress fibers and cytokinesis. This protein is involved in lamellipodia and filopodia formation in motile cells and may affect neuronal growth-cone guidance. This protein has also been identified as interacting with the dentatorubral-pallidoluysian atrophy gene, which is associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.

Carrier-free (BSA/glycerol-free) BAIAP2 mouse monoclonal antibody, clone LBI8G8

BAP2; FLAF3; IRSP53

Homo sapiens BAR/IMD domain containing adaptor protein 2 (BAIAP2), transcript variant 3, mRNA.

10458

Q9UQB8

Unconjugated

Adherens junction, Regulation of actin cytoskeleton

Adherens junction, Regulation of actin cytoskeleton

WB 1:2000, IHC 1:150, IF 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

BAIAP2

https://www.ncbi.nlm.nih.gov/gene/?term=10458

https://www.uniprot.org/uniprot/Q9UQB8