Bat coronavirus Anlong103 Spike Trimer Protein (R645A, K946P, V947P), zijn tag (MALS geverifieerd)

The spike protein of bat coronavirus Anlong103, a SARS-CoV-2–related sarbecovirus identified in bats from China’s Guizhou province, mediates viral entry by facilitating receptor attachment and membrane fusion. While closely related to other bat coronaviruses, Anlong103’s spike shows distinct structural features that may limit human ACE2 binding, yet retains conserved antigenic sites. These characteristics make it valuable for studying cross-species transmission potential and coronavirus evolution in wildlife reservoirs.

The spike protein of bat coronavirus Anlong103, a SARS-CoV-2–related sarbecovirus identified in bats from China’s Guizhou province, mediates viral entry by facilitating receptor attachment and membrane fusion. While closely related to other bat coronaviruses, Anlong103’s spike shows distinct structural features that may limit human ACE2 binding, yet retains conserved antigenic sites. These characteristics make it valuable for studying cross-species transmission potential and coronavirus evolution in wildlife reservoirs.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 133.5 kDa. The protein migrates as >160 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Asp 14 - Pro 1173

Spike protein

Unconjugated

C-10xHis

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

1.0 EU per μg

90%

Powder

0.1 M Sodium citrate, pH5.5

133.5 kDa

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RT

-20°C

100ug*1

HEK293

Bat coronavirus Anlong103

A0A1W5YKT9 (R645A, K946P, V947P)

Trehalose