Bat coronavirus BANAL20-236 Spike Trimer Protein (R677A, K978P, V979P), zijn tag (MALS geverifieerd)
Gecertificeerd

Bat coronavirus BANAL20-236 Spike Trimer Protein (R677A, K978P, V979P), zijn tag (MALS geverifieerd)

Catalog #: SPN-S522d-100ug
Maat: 100 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Technische Documentatie

Technische Specificaties

Background

The spike protein of bat coronavirus BANAL-20-236, a SARS-CoV-2–related sarbecovirus identified in Laos, mediates viral entry by promoting receptor attachment and membrane fusion. BANAL-20-236 shares high genomic similarity with SARS-CoV-2 and contains spike features relevant to cross-species transmission. Specific substitutions, such as P804L in the S2 subunit, have been linked to adaptation to a broad range of Rhinolophus bat ACE2 receptors, making it important for studies on coronavirus evolution and zoonotic spillover risk.

Description

The spike protein of bat coronavirus BANAL-20-236, a SARS-CoV-2–related sarbecovirus identified in Laos, mediates viral entry by promoting receptor attachment and membrane fusion. BANAL-20-236 shares high genomic similarity with SARS-CoV-2 and contains spike features relevant to cross-species transmission. Specific substitutions, such as P804L in the S2 subunit, have been linked to adaptation to a broad range of Rhinolophus bat ACE2 receptors, making it important for studies on coronavirus evolution and zoonotic spillover risk.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 137.3 kDa. The protein migrates as >130 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) .

Expression Region

Ser 14 - Pro 1205

Target

Spike protein

Conjugation

Unconjugated

Tag

C-10xHis

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

1.0 EU per μg

Purity

90%

Format

Powder

Buffer

0.1 M Sodium citrate, pH5.5

Molecular Weight

137.3 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Host or Source

HEK293

Species

Bat coronavirus BANAL20-236

Protein ID

UAY13253.1 (R677A, K978P, V979P)

Preservative

Trehalose

Beschrijving

The spike protein of bat coronavirus BANAL-20-236, a SARS-CoV-2–related sarbecovirus identified in Laos, mediates viral entry by promoting receptor attachment a

Specificaties

ProductnaamBat coronavirus BANAL20-236 Spike Trimer Protein (R677A, K978P, V979P), zijn tag (MALS geverifieerd)
Categorie
Beschikbare grootte100 µg
CatalogusnummerSPN-S522d-100ug