BAY-876
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent inhibitor (IC50 = 2 nM) of the facilitative glucose transporter GLUT1, an enzyme frequently overexpressed in many cancers.1 It shows greater than 100-fold selectivity over GLUT2-4. BAY-876 displayed potent antitumor activity in ovarian cancer xenograft models2 and in triple negative breast cancer cells displaying high glycolytic and low oxidative phosphorylation rates3. It reduced CD4+ T cell proliferation and IFN-γ secretion via GLUT1 inhibition suggesting utility against auto-inflammatory diseases.4 BAY-876 induces disulfidptosis in SLCA11high cancer cells.5
Unconjugated
White solid
-20°C
Beschrijving
BAY-876 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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