Bay-X-7195
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Bay-X-7195 is a CYS leukotriene 1 receptor (CYS LT1) antagonist. Bay-X-7195 shows an antagonistic action to LTD4-induced bronchoconstriction in vitro and in vivo. Bay-X-7195 can be used foe the study of allergic and asthmatic[1][2].
143538-27-6
12352005
Leukotriene Receptor
GPCR/G Protein
Inflammation/Immunology
O=C(O)C1=CC=C(S[C@@H](CCC(O)=O)/C=C\CC2=CC=C(OCCCCOC3=CC=CC=C3)C=C2)C=C1
C30H32O6S
520.64
[1]Boulet LP, et al. Inhibitory effects of BAY x 7195, a CYS leukotriene 1 receptor antagonist, on allergen-induced asthmatic responses. Ann Allergy Asthma Immunol. 1997 Aug;79 (2) :155-61. |[2]Tanaka H, et al. The effect of a novel leukotriene C4/D4 antagonist, BAY-x-7195, on experimental allergic reactions. Prostaglandins. 1995 Nov-Dec;50 (5-6) :269-85.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-19161/
Reference compound1
Phase 2
Beschrijving
Bay-X-7195 is a CYS leukotriene 1 receptor (CYS LT1) antagonist. Bay-X-7195 shows an antagonistic action to LTD4-induced bronchoconstriction in vitro and in viv
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