BAY1125976
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1402608-02-9
C13452-5mg
Akt
PI3K/Akt/mTOR
C1CC (C1) (C2=CC=C (C=C2) C3=C (N4C (=N3) C=CC (=N4) C (=O) N) C5=CC=CC=C5) N
C23H21N5O
BAY 1125976 is a selective allosteric AKT1/2 inhibitor, exhibits high efficacy on AKT signaling-dependent tumor growth in mouse models. BAY1125976 inhibits the activity of AKT1 (IC50 = 5.2 nM at 10 μM ATP and 44 nM at 2 mM ATP) and AKT2 (IC50 = 18 nM at 10 μM ATP and 36 nM at 2 mM ATP) very potently.Whereas BAY1125976 is almost inactive on AKT3 (IC50 = 427 nM at 10 μM ATP) .
3 years -20°C powder
Beschrijving
BAY1125976 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
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