
BBI-2779
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
2871057-47-3
C18316-5mg
Chk
Cell Cycle
COC1=CC=CC (O[C@H]2[C@@H] (CC2) N) =C1C3=CC (NC4=NC=C (C#N) N=C4) =NN3
C19H19N7O2
BBI-2779 is a potent, selective, and orally active inhibitor of CHK1 with an IC50 of 0.3 nM. It preferentially kills cancer cells containing extrachromosomal DNA (ecDNA) by inducing replication stress and cell death. In gastric cancer models with FGFR2 gene amplification on ecDNA, BBI-2779 suppresses tumor growth and prevents drug resistance.
Beschrijving
BBI-2779 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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