BBS10 Antilichaam - C-terminal regio : FITC (ARP59803 P050-FITC)

Bardet-Biedl syndrome 10

C12orf58

79738

Q8TAM1

NP_078961

Human, Rabbit

The immunogen is a synthetic peptide directed towards the C terminal region of human BBS10

This gene is a member of the Bardet-Biedl syndrome (BBS) gene family. Bardet-Biedl syndrome is an autosomal recessive disorder characterized by progressive retinal degeneration, obesity, polydactyly, renal malformation and mental retardation. The proteins encoded by BBS gene family members are structurally diverse and the similar phenotypes exhibited by mutations in BBS gene family members is likely due to their shared roles in cilia formation and function. Many BBS proteins localize to the basal bodies, ciliary axonemes, and pericentriolar regions of cells. BBS proteins may also be involved in intracellular trafficking via microtubule-related transport. The protein encoded by this gene is likely not a ciliary protein but rather has distant sequence homology to type II chaperonins. As a molecular chaperone, this protein may affect the folding or stability of other ciliary or basal body proteins. Inhibition of this protein's expression impairs ciliogenesis in preadipocytes. Mutations in this gene cause Bardet-Biedl syndrome type 10.

UBC; YAE1D1; MAPK8IP2; HDAC6; TNFSF11; MAP3K7; RGS2; RASA1; PTK2; MAPK6; NR4A1; FRZB; CSNK1E

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

BBS10 is supported by BioGPS gene expression data to be expressed in HEK293T

0.5 mg/ml

Human: 100%; Rabbit: 86%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

81kDa

Wet Ice

723

BBS10

BBS10

Rabbit

Bardet-Biedl syndrome 10 protein

NM_024685

SQTGLESVMGKYQLLTSVLQCLTKILTIDMVITVKRHPQKVHNQDSEDEL