BBTF2 Antilichaam - N-terminalgebied: FITC (ARP47711_P050-FITC)

Basic leucine zipper transcription factor, ATF-like 2

SARI

116071

Q8N1L9

Human, Yeast

The immunogen is a synthetic peptide directed towards the N-terminal region of Human BATF2

BATF2 is a AP-1 family transcription factor that controls the differentiation of lineage-specific cells in the immune system. Following infection, it participates in the differentiation of CD8 (+) thymic conventional dendritic cells in the immune system. It acts via the formation of a heterodimer with JUN family proteins that recognizes and binds DNA sequence 5'-TGA[CG]TCA-3' and regulates expression of target genes (By similarity) . It selectively suppresses CYR61/CCN1 transcription and hence blocks the downstream cell proliferation signals produced by CYR61 and inhibits CYR61-induced anchorage-independent growth and invasion in several cancer types, such as breast cancer, malignant glioma and metastatic melanoma. It possibly acts by interfering with AP-1 binding to CYR61 promoter.

DAZAP2; MAFF; JUNB; JUN; EPAS1; DDIT3; DBP; CEBPG; CEBPE; CEBPA; ATF4; C2orf88; DEDD; RELA; HLA-C; KAT2A; ATXN1

FITC: Fluorescein Isothiocyanate

Polyclonal Antibody

WB

Affinity Purified

0.5 mg/ml

Human: 100%; Yeast: 77%

Liquid. Purified antibody supplied in 1x PBS buffer.

All conjugated antibodies should be stored in light-protected vials or covered with a light protecting material (i.e. aluminum foil) . Conjugated antibodies are stable for at least 12 months at 4C. If longer storage is desired (24 months), conjugates may be diluted with up to 50% glycerol and stored at -20C to -80C. Freezing and thawing conjugated antibodies will compromise enzyme activity as well as antibody binding.

30kDa

Wet Ice

274

BATF2

BATF2

Rabbit

Basic leucine zipper transcriptional factor ATF-like 2

CGGNGLLTQTDPKEQQRQLKKQKNRAAAQRSRQKHTDKADALHQQHESLE