BCA-1
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-1/BLC is a potent chemoattractant for B lymphocytes and induces weak chemotactic response in T cells and macrophages. It manifests no activity on neutrophils and monocytes. Recombinant Human BCA-1 is a 10.3 kDa protein containing 87 amino acid residues including the four highly conserved cysteine residues present in CXC chemokines.
CXCL13; BLC; BCA1; ANGIE; BCA-1; BLR1L; ANGIE2; SCYB13
10563
O43927
NP_006410.1
NM_006419.2
4q21
Human
Human
VLEVYYTSLR CRCVQESSVF IPRRFIDRIQ ILPRGNGCPR KEIIVWKKNK SIVCVDPQAE WIQRMMEVLR KRSSSTLPVP VFKRKIP
< 0.1 ng/µg of protein (< 1EU/µg)
> 98% by SDS-PAGE & HPLC analyses
The biological activity of human BCA-1 was determined by chemotaxis assay using human B cells. Significant chemotaxis was achieved at a concentration range of 1.0-10 ng/ml.
87
Lyophilized
10.3 kDa
E. coli
Beschrijving
BCA-1/BLC, a CXC chemokine, is expressed in the liver, spleen, lymph nodes, appendix and stomach. It exerts its activities through its only receptor CXCR5. BCA-
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