Bcl-2 Antilichaam [10C4]

Bcl-2 is a 26 kDa member of the family of proteins involved in regulation of programmed cell death, or apoptosis. It is expressed in a variety of both normal and neoplastic tissues and appears to be membrane-bound since it is detectable in crude membrane and nuclear fractions, but not in the soluble fraction of cell lysates. Overexpression of Bcl-2 can prevent apoptosis, while formation of heterodimers with Bax, another Bcl-2-related protein, inhibits Bcl-2’s ability to promote cell survival.

12043;24224

P10417

P10417

Mouse, Rat

Murine Bcl-2 peptide (a.a. 61-76)

[10C4]

Unconjugated

Primary Antibodies

Cancer, Obesity, Signal Transduction

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG1

Bcl-2

Bcl-2 Antibody [10C4] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, and immunoprecipitation assays.

Bcl2

B cell leukemia/lymphoma 2

Mus musculus

B cell leukemia 2

Flow

Liquid