Bcl-xL Antilichaam [7B2.5]

Bcl-xL is a 29 kDa member of the Bcl-2 family of proteins involved in regulation of programmed cell death, or apoptosis. It is found in both soluble and membrane fractions of cellular lysates. Like Bcl-2, Bcl-xL has been demonstrated to block apoptosis which is induced by a variety of stimuli and, under certain conditions, offers greater protection against apoptosis than Bcl-2. While formation of heterodimers with the apoptosis-enhancing protein, Bax does not block the apoptosis-suppressing property of Bcl-xL, heterodimerization with Bad effectively inhibits the protective function of Bcl-xL.

598

Q07817

Q07817

Human, Mouse, Rat, Rhesus Monkey

Recombinant human Bcl-xS

[7B2.5]

Unconjugated

Primary Antibodies

Transcription, Cancer

0.1 mg/mL

Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

None

Blue Ice

Store vial at 2-8˚ C

IgG3

Bcl-xL

Bcl-xL Antibody [7B2.5] for use in flow cytometry, immunohistochemistry / immunocytochemistry, ELISA, western blotting, and immunoprecipitation assays.

BCL2L1

BCL2-like 1

Homo sapiens

Apoptosis regulator Bcl-X, Bcl-2-like 1 protein, BCL2L1

Flow

Liquid