Bcr (Ab 177) Antilichaam

GTPase-activating protein for RAC1 and CDC42. Promotes the exchange of RAC or CDC42-bound GDP by GTP, thereby activating them. Displays serine/threonine kinase activity.

613

P11274

NP_004318.3

Human, Mouse

Bcr (Ab-177) antibody was raised against a peptide sequence around aa. 175~179 (P-F-Y-V-N) derived from Human Bcr.

Unconjugated

Primary Antibodies

Cell Cycle

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

130, 160, 210 kDa

This antibody detects endogenous level of total Bcr protein.

Western Blot: 1:500~1:1000, Immunofluorescence: 1:100~1:200

BCR

Breakpoint cluster region

Homo sapiens

Sattler M, et al. Mol Cell Biol. 1999 Nov; 19 (11) : 7473-7480. Li S et al. EMBO J. 2001 Dec 3; 20 (23) : 6793-6804. Million RP, et, al. Mol Cell Biol. 2004 Jun; 24 (11) : 4685-4695. Malcolm A. Meyn, et al. . Biol. Chem., Oct 2006; 281: 30907 – 30916.

ALL, CML, PHL, BCR1, D22S11, D22S662, MAPTL, MTBT1, TAU, Renal carcinoma antigen NY-REN-26

WB, IF

82546843

Liquid