BCY8234

2922478-12-2

BCY8234 is an analogue of BT8009 that does not contain MMAE. BT8009 is a toxin conjugate targeting nectin-4, utilized in the treatment of solid tumors. BCY8234 can reduce the response to BT8009.

C(C=1C=2C(NC1)=CC=CC2)[C@@H]3NC(=O)[C@]4(N(C(=O)[C@]5(N(C(=O)[C@]([C@@H](C)O)(NC(=O)[C@H](CO)NC(=O)[C@H](CC=6C=7C(NC6)=CC=CC7)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](CCCCNC(=N)N)NC(=O)[C@H](CCSC)NC(=O)[C@@]8(CSCCC(=O)N9CN(C(=O)CCSC[C@@H](C(N)=O)NC3=O)CN(C9)C(=O)CCSC[C@H](NC(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CN(C(CCN)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C)=O)C(=O)N%10[C@](C(=O)N[C@@H](CC=%11C%12=C(C=CC%11)C=CC=C%12)C(=O)N[C@H](CC(O)=O)C(=O)N8)(CCC%10)[H])[H])[H])CCC5)[H])C[C@H](O)C4)[H]

C131H185N35O36S4

2954.34

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