BDPI

BDPI is the a BODIPY derivative. BDPI reveals a high O2 quantum yield and exhibits phototoxicity that inhibits HeLa with an IC50 of 0.6 µg/mL. BDPI nanoarticles can be taken up by HeLa, producing fluorescence signals in the cells, and can be used as cell imaging agent. BDPI nanoarticles exhibit antitumor efficacy in mouse models[1].

1083009-44-2

12352005

H302, H315, H319, H335

Fluorescent Dye; Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB; Others

Cancer

98.10

CC(C(I)=C1C)=C(N1[B-]2(F)F)C(C3=CC=CC=C3)=C4[N+]2=C(C)C(I)=C4C

C19H17BF2I2N2

575.97

H302, H315, H319, H335

[1]Zou J, et al., BODIPY Derivatives for Photodynamic Therapy: Influence of Configuration versus Heavy Atom Effect. ACS Appl Mater Interfaces. 2017 Sep 27;9 (38) :32475-32481.

Room Temperature

4°C (Powder, sealed storage, away from moisture and light)

http://file.medchemexpress.com/batch_PDF/HY-W112239/

Reference compound1

No Development Reported