Belactine A
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Belactin A (Compound 4) is a Carboxypeptidase Y (CP-Y) inhibitor with a IC50 of 0.18 μM. Belactin A can be isolated from Streptomyces erythraeus. Belactin A has antihypertensive and general pump inhibitory activities[1][2].
175448-24-5
12352005
Carboxypeptidase
Metabolic Enzyme/Protease
Cardiovascular Disease
O=C(C1=C(C=CC(Cl)=C1)N)N[C@@H](C)C(C(C)([C@H]2[C@@H](C(O2)=O)C)C)=O
C17H21ClN2O4
352.81
[1]Murakami S, et al. The absolute configuration of belactin A, a beta-lactone-containing serine carboxypeptidase inhibitor: importance of the beta-lactone structure for serine carboxypeptidase inhibition. J Enzyme Inhib. 1999;14 (6) :437-46.|[2]Vil V, et al. Oxetane-containing metabolites: origin, structures, and biological activities. Appl Microbiol Biotechnol. 2019 Mar;103 (6) :2449-2467.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-N16373/
Natural Products
No Development Reported
Beschrijving
Belactin A (Compound 4) is a Carboxypeptidase Y (CP-Y) inhibitor with a IC50 of 0.18 μM. Belactin A can be isolated from Streptomyces erythraeus. Belactin A has
Specificaties
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