Belantamab (FUT8-KO)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Belantamab (FUT8-KO) is an anti-BCMA (TNFRSF17) monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficiency enhances the ADCC effect of the antibody. Belantamab (FUT8-KO) can be used to synthesize antibody-active molecule conjugate (ADC), Belantamab mafodotin[1].
12352203
ADC Antibody; TNF Receptor
Antibody-drug Conjugate/ADC Related; Apoptosis
Cancer-programmed cell death
Cancer
98.10
[Belantamab(FUT8-KO)]
(146.06 kDa)
[1]Ivo Demel, et al. Focus on monoclonal antibodies targeting B-cell maturation antigen (BCMA) in multiple myeloma: update 2021. Br J Haematol. 2021 May;193 (4) :705-722.
Dry Ice
Store at -80°C for 2 years
http://file.medchemexpress.com/batch_PDF/HY-P9980A/Belantamab-FUT8-KO-SDS-MedChemExpress.pdf
Inhibitory Antibodies
No Development Reported
Beschrijving
Belantamab (FUT8-KO) is an anti-BCMA (TNFRSF17) monoclonal antibody expressed by CHO cells with the fucosyltransferase 8 gene (FUT8) knocked out. Fucose deficie
Specificaties
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