Benzocaïne (hydrochloride) (standaard)
Gecertificeerd

Benzocaïne (hydrochloride) (standaard)

Catalog #: HY-Y0258AR-01
Maat: 10 mg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

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Gratis verzending vanaf €100

Technische Specificaties

Description

Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain, that acts on voltage-gated Na+ channels at a common receptor, with an IC50 value of 0.8 mM at +30 mV. Additionally, Benzocaine (hydrochloride) non-competitively inhibits Ca-ATPase binding with Ca2+, with an IC50 of 47.1 mM. Benzocaine (hydrochloride) can be used in research within the field of neuromuscular regulation[1][2][3].

CAS Number

23239-88-5

UNSPSC

12352005

Target

Bacterial; Sodium Channel

Related Pathways

Anti-infection; Membrane Transporter/Ion Channel

Field of Research

Neurological Disease

Smiles

O=C(OCC)C1=CC=C(N)C=C1.[H]Cl

Molecular Formula

C9H12ClNO2

Molecular Weight

201.65

References & Citations

[1]Wang GK, et al. A common local anesthetic receptor for benzocaine and etidocaine in voltage-gated mu1 Na+ channels. Pflugers Arch. 1998 Jan;435 (2) :293-302.|[2]Davis JA, et al. Benzocaine-induced methemoglobinemia attributed to topical application of the anesthetic in several laboratory animal species. Am J Vet Res. 1993 Aug;54 (8) :1322-6.|[3]Di Croce D, et al. Drug action of benzocaine on the sarcoplasmic reticulum Ca-ATPase from fast-twitch skeletal muscle. Naunyn Schmiedebergs Arch Pharmacol. 2015 Nov;388 (11) :1163-70.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-Y0258AR/

Scientific Category

Reference Standards

Beschrijving

Benzocaine (hydrochloride) is an orally active local agent that can suppress or relieve pain, that acts on voltage-gated Na+ channels at a common receptor, with

Specificaties

ProductnaamBenzocaïne (hydrochloride) (standaard)
Categorie
Beschikbare grootte10 mg
CatalogusnummerHY-Y0258AR-01