Benzofenon-2
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Benzophenone-2 (2,2',4,4'-Tetrahydroxybenzophenone) is an endocrine disruptor targeting pregnane X receptor (PXR) and estrogen receptor α (ERα) . Benzophenone-2 regulates cytochrome P450 3A (CYP3A) expression by activating PXR. Benzophenone-2 is promising for research of UV filters[1][2].
131-55-5
2,2′,4,4′-Tetrahydroxybenzophenone
12352005
H302, H317, H319
Estrogen Receptor/ERR; Pregnane X Receptor (PXR)
Vitamin D Related/Nuclear Receptor
Metabolism-protein/nucleotide metabolism
Others
99.68
DMSO : 100 mg/mL (ultrasonic)
O=C(C1=CC=C(O)C=C1O)C2=CC=C(O)C=C2O
C13H10O5
246.22
H302, H317, H319
[1]Hu X, et al. Evaluation of polyhydroxybenzophenones as α-glucosidase inhibitors. Arch Pharm (Weinheim) . 2011 Feb;344 (2) :71-7.|[2]Casiano-Muñiz IM, et al. UV filter benzophenone-2: Effects on zebrafish (Danio rerio) cytochrome P450. Aquat Toxicol. 2024 Aug;273:106973.
Room Temperature
RT, stored under nitrogen
http://file.medchemexpress.com/batch_PDF/HY-W036120/Benzophenone-2-SDS-MedChemExpress.pdf
Reference compound2
No Development Reported
Beschrijving
Benzophenone-2 (2,2',4,4'-Tetrahydroxybenzophenone) is an endocrine disruptor targeting pregnane X receptor (PXR) and estrogen receptor α (ERα) . Benzophenone-2
Specificaties
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