Beta-Actin Antilichaam

Beta-Actin Antibody: Actins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. Beta actin is one of six different actin isoforms which have been identified. Like GAPDH, beta-Actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.

60

P60709

AAH02409

Human, Mouse, Rat

B-actin antibody was raised against a 16 amino acid synthetic peptide from near the amino-terminus of human b-actin.

Unconjugated

Primary Antibodies

Homeostasis

Beta-Actin Antibody is affinity chromatography purified via peptide column.

Cat. No. 1201 - HeLa Cell Lysate

1 mg/mL

Beta-Actin Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

Beta-Actin antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

ACTB

Actin, beta

Homo sapiens

Lambrechts A, Van Troys, M and Ampe C. The actin cytoskeleton in normal and pathological cell motility. Int. J. Biochem. Cell Biol. 2004; 36:1890-909.

Gourlay CW and Ayscough KR. The actin cytoskeleton: a key regulator of apoptosis and ageing. Nat. Rev. 2005; 6:583-9.

Beta-Actin Antibody: Beta actin, b actin

ELISA, WB, IHC, IF

12803203

Liquid