Beta-Zearanalol-d5

Beta-Zearalanol-d5 is the deuterium labeled Beta-Zearalanol. Beta-Zearalenol is an mycotoxin produced by Fusarium spp, which causes apoptosis and oxidative stress in mammalian reproductive cells[1]. Beta-Zearalenol is the derivative of Zearalenone (HY-103447) which can conjugate with glucuronic acid[2].

12352005

Apoptosis; Isotope-Labeled Compounds

Apoptosis; Others

Metabolism-protein/nucleotide metabolism

Metabolic Disease

OC1=C2C(CCCCC([2H])([2H])[C@](C([2H])([2H])CC[C@@H](OC2=O)C)([2H])O)=CC(O)=C1

C18H21D5O5

327.43

[1]Yang F, et al. Melatonin alleviates β-zearalenol and HT-2 toxin-induced apoptosis and oxidative stress in bovine ovarian granulosa cells. Environ Toxicol Pharmacol. 2019 May;68:52-60. |[2]Marin DE, et al. Cytotoxic and inflammatory effects of individual and combined exposure of HepG2 cells to zearalenone and its metabolites. Naunyn Schmiedebergs Arch Pharmacol. 2019 Aug;392 (8) :937-947.

Room Temperature

-20°C, 3 years; 4°C, 2 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-N6740S2/

Isotope-Labeled Compounds

No Development Reported