Betavulgarine

Betavulgarin is an anticancer agent. Betavulgarin can be isolated from Sugar Beet (Beta vulgaris) . Betavulgarin suppresses the proliferation, migration, colony formation, and mammosphere formation of breast cancer cells, and reduces the size of the CD44+/CD24− subpopulation and the expression of the self-renewal- related genes C-Myc, Nanog and Oct4. Betavulgarin promotes BCSCs death through the regulation of Stat3/Sox2 signaling[1].

51068-94-1

12352005

STAT

JAK/STAT Signaling; Stem Cell/Wnt

Cancer-Kinase/protease

Cancer

O=C1C(C2=C(O)C=CC=C2)=COC3=C1C(OC)=C4OCOC4=C3

C17H12O6

312.27

[1]Liu R, et al. Betavulgarin Isolated from Sugar Beet (Beta vulgaris) Suppresses Breast Cancer Stem Cells through Stat3 Signaling. Molecules. 2020 Jun 30; 25 (13) :2999.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-N15201/

Natural Products

No Development Reported

STAT3