BG-DBCO
Gecertificeerd

BG-DBCO

Catalog #: HY-W1124386
Maat: 1 Each

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
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Gratis verzending vanaf €100

Technische Specificaties

Description

BG-DBCO is a DBCO-conjugated Benzylguanine. BG-DBCO, SNAP-E3 fusion protein and Ligand-N3 form a protein complex. BG-DBCO is conjugated with JQ1-N3-C10 to obtain BG-JQ1. BG-JQ1, administered together with SIAH1-SN mRNA, effectively inhibits the growth of small cell carcinoma of the adrenocortical gland[1].

CAS Number

1820756-74-8

Product Name Alternative

SNAP-DBCO

UNSPSC

12352005

Target

Drug Derivative; Drug Intermediate

Related Pathways

Others

Field of Research

Cancer

Smiles

NC1=NC2=C(C(OCC3=CC=C(C=C3)CNC(CCC(N4CC5=C(C#CC6=CC=CC=C46)C=CC=C5)=O)=O)=N1)N=CN2

Molecular Formula

C32H27N7O3

Molecular Weight

557.60

References & Citations

[1]Teng X, et al. ClickRNA-PROTAC for Tumor-Selective Protein Degradation and Targeted Cancer Therapy. J Am Chem Soc. 2024 Oct 9;146 (40) :27382-27391.

Shipping Conditions

Room temperature

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W1124386/

Scientific Category

Dye Reagents

Clinical Information

No Development Reported

Beschrijving

BG-DBCO is a DBCO-conjugated Benzylguanine. BG-DBCO, SNAP-E3 fusion protein and Ligand-N3 form a protein complex. BG-DBCO is conjugated with JQ1-N3-C10 to obtai

Specificaties

ProductnaamBG-DBCO
Categorie
Beschikbare grootte1 Each
CatalogusnummerHY-W1124386