
BG45
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Potent and selective HDAC3 inhibitor (IC50 = 289 nM), IC50s for HDAC1, 2 and 6 = 2, 2.2 and >20 mM respectively.1 Inhibits tumor growth in a mouse xenograft model of human multiple myeloma.1 Downregulates expression of DNA methyltransferase 1.2 Increases expression of synaptic proteins in exogenous Aβ-treated cells and mice.3 Rescues synaptic damage and neuron loss in APP-transfected cells (15 mM) and APP/PS1 mice (30 mg/kg) .4
Unconjugated
Beige solid
-20°C
Beschrijving
BG45 Beschikbaar in 5 mg. Bestel eenvoudig online met snelle levering.
Specificaties
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