BGLAP Antilichaam

This gene encodes a highly abundant bone protein secreted by osteoblasts that regulates bone remodeling and energy metabolism. The encoded protein contains a Gla (gamma carboxyglutamate) domain, which functions in binding to calcium and hydroxyapatite, the mineral component of bone. Serum osteocalcin levels may be negatively correlated with metabolic syndrome. Read-through transcription exists between this gene and the neighboring upstream gene, PMF1 (polyamine-modulated factor 1), but the encoded protein only shows sequence identity with the upstream gene product.

632

P02818

Human, Mouse

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BGLAP (NP_954642.1) .

Unconjugated

Primary Antibodies

Cell Cycle, Signal Transduction, Stem Cell

Affinity purification

U-251MG

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 11kDa

IgG

WB: 1:500 - 1:2000

BGLAP

Mouse pancreas

Bone gamma-carboxyglutamate (gla) protein

Homo sapiens

BGLAP, bone gamma-carboxyglutamate (gla) protein, BGP, OC, OTTHUMP00000016586, bone Gla protein, bone gamma-carboxyglutamate (gla) protein (osteocalcin), gamma-carboxyglutamic acid-containing protein, osteocalcin

WB

Liquid