BI-1808
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BI-1808 is a human IgG1 monoclonal antibody that targets TNFR2by blocking interaction of TNFR2 with ligand TNF-α, confers FcγR-dependent depletion of Treg and mediates expansion of intratumoral CD8+ T cells[1].
12352203
TNF Receptor
Apoptosis
Cancer-programmed cell death
Cancer
97.75
(144.206 kDa)
[1]Kristoffer Staahl Rohrberg1, et al. 757 Phase 1/2a clinical trial of BI-1808, a monoclonal antibody to tumor necrosis factor receptor 2 (TNFR2) as single agent and in combination with pembrolizumab. J Immunother Cancer 2023;11 (Suppl 1) :A1–A1731
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991192/BI-1808-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 2
Beschrijving
BI-1808 is a human IgG1 monoclonal antibody that targets TNFR2by blocking interaction of TNFR2 with ligand TNF-α, confers FcγR-dependent depletion of Treg and m
Specificaties
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hsa-miR-4258 miRNA Mimic
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hsa-miR-1258 miRNA Agomir
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Hsa-miR-1258 miRNA Mimic
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Hsa-miR-4258 miRNA Mimic
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Hsa-miR-4258 miRNA Agomir
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5 nmol