BI-D1870
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
501437-28-1
C08901-5mg
S6 Kinase
MAPK
CC1C (=O) N (C2=CN=C (N=C2N1CCC (C) C) NC3=CC (=C (C (=C3) F) O) F) C
C19H23F2N5O2
BI-D1870 is an ATP-competitive inhibitor of S6 ribosome for RSK1/2/3/4 with IC50 of 31 nM/24 nM/18 nM/15 nM in cell-free assays, respectively; 10- to 100-fold selectivity for RSK than MST2, GSK-3β, MARK3, CK1 and Aurora B. BI-D1870 exhibits anticancer attributes including the generation of reactive oxygen species (ROS) and increases in endoplasmic reticulum (ER) stress and autophagy.
2 years -80 in solvent
Beschrijving
BI-D1870 Beschikbaar in 5 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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