Bicyclische UK18
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Bicyclic UK18 is a competitive inhibitor for human urokinase-type plasminogen activator (uPA) with a Ki of 53 nM[1].
1393680-45-9
12352209
PAI-1
Metabolic Enzyme/Protease
Cancer
O=C([C@@H](N)C)N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H](C(N[C@H](C(NCC(O)=O)=O)CSC1)=O)C)=O)CO)=O)=O)CCCNC(N)=N)=O)=O)CCCNC(N)=N)=O)CSC2)=O)CC(O)=O)=O)C(C)C)=O)CCC(O)=O)=O)CC3=CC=C(O)C=C3)=O)CCCNC(N)=N)=O)CO)=O)CSCC4=CC2=CC1=C4
C77H118N26O25S3
1904.12
[1]Angelini A, et al., Bicyclic peptide inhibitor reveals large contact interface with a protease target. ACS Chem Biol. 2012 May 18;7 (5) :817-21.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P10877/
Peptides
No Development Reported
Beschrijving
Bicyclic UK18 is a competitive inhibitor for human urokinase-type plasminogen activator (uPA) with a Ki of 53 nM[1].
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