Bifenazaat-d5

Bifenazate-d5 is the deuterium labeled Bifenazate. Bifenazate is a carbazate acaricide that control 100% of mites at a concentration of 25 ppm[1]. Bifenazate is a positive allosteric modulator of GABA receptor[2]. Bifenazate is the inhibitor for the mitochondrial electron transport chain complex III[3].

12352005

Reactive Oxygen Species (ROS)

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Infection

COC(C=CC(C1=C(C([2H])=C(C([2H])=C1[2H])[2H])[2H])=C2)=C2NNC(OC(C)C)=O

C17H15D5N2O3

305.38

[1]Dekeyser, M.A., McDonald, P.T., and Angle, G.W., Jr. The discovery of bifenazate, a novel carbazate acaricide Chimia 57 (11), 702-704 (2003) .|[2]Hiragaki S, et al. A novel action of highly specific acaricide; bifenazate as a synergist for a GABA-gated chloride channel of Tetranychus urticae [Acari: Tetranychidae]. Neurotoxicology. 2012 Jun;33 (3) :307-13.|[3]Ma J, et al., Bifenazate exposure induces cardiotoxicity in zebrafish embryos. Environ Pollut. 2021 Apr 1;274:116539.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W725476/

Isotope-Labeled Compounds

No Development Reported