BIIB022
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BIIB022 is a human IgG4 monoclonal antibody (mAb) targeting IGF1R/CD221. BIIB022 blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R and downstream substrates. BIIB022 can be used in lung, pancreatic, and colon cancer research. Recommended isotype control: Human IgG4 kappa, Isotype Control.
12352203
IGF-1R
Protein Tyrosine Kinase/RTK
Cancer-Kinase/protease
Cancer
[1]von Mehren M, et al. A phase 1, open-label, dose-escalation study of BIIB022 (anti-IGF-1R monoclonal antibody) in subjects with relapsed or refractory solid tumors. Invest New Drugs. 2014 Jun;32 (3) :518-25.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991253/
Inhibitory Antibodies
No Development Reported
Beschrijving
BIIB022 is a human IgG4 monoclonal antibody (mAb) targeting IGF1R/CD221. BIIB022 blocks IGF-1 and IGF-2-induced phosphorylation of IGF-1R and downstream substra
Specificaties
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