Bijlage A13 Polyklonale Antilichaam, AbBy FluorTM 555 Vervoeging

The Annexins constitute a family of structurally-related, relatively abundant proteins that exhibit Ca2+-dependent binding to phospholipids. Annexins function in multiple aspects of cell biology including regulation of membrane trafficking, transmembrane channel activity, inhibition of phospholipase A2, inhibition of coagulation and mediation of cell-matrix interactions. Annexin A13 is considered the original progenitor of the 12 members of vertebrate Annexins. The expression of Annexin A13 is highly tissue-specific, being expressed only in intestinal and kidney epithelial cells. This expression is associated with a highly differentiated intracellular transport function. Two alternative splicing isoforms of Annexin A13 exist, both of which bind to rafts.

ISA; ANX13; Annexin A13; Annexin XIII; Annexin-13; Intestine-specific annexin; ANXA13

312

P27216

Cytoplasm, Cell membrane

Human

241-316/316

Annexin A13

AbBy Fluor™ 555

KLH conjugated synthetic peptide derived from human Annexin A13

WB, IF (IHC-P), IF (IHC-F), IF (ICC)

Purified by Protein A.

553nm/568nm

1µg/µl

WB (1:300-5000), IF (IHC-P) (1:50-200), IF (IHC-F) (1:50-200), IF (ICC) (1:50-200)

Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Unmodified

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

312

Mouse, Rat, Dog, Horse, Rabbit