Bimatoprostcyclohexylamide

Bimatoprost cyclohexyl amide (N-Cyclohexyl-desamethyl bimatoprost; 17-Phenyl trinor prostaglandin F2α cyclohexyl amide) is an analog of bimatoprost. Bimatoprost cyclohexyl amide is an agonist of the prostaglandin F2α receptor. Bimatoprost cyclohexyl amide is used in research on reducing intraocular pressure and glaucoma[1][2].

N-Cyclohexyl-desamethyl bimatoprost; 17-Phenyl trinor prostaglandin F2α cyclohexyl amide

12352005

Prostaglandin Receptor

GPCR/G Protein

Endocrinology

O[C@H](/C=C/[C@H]1[C@@H](C[C@@H]([C@@H]1C/C=C\CCCC(NC2CCCCC2)=O)O)O)CCC3=CC=CC=C3

C29H43NO4

469.66

[1]Balapure AK, et al. Structural requirements for prostaglandin analog interaction with the ovine corpus luteum prostaglandin F2 alpha receptor. Implications for development of a photoaffinity probe. Biochem Pharmacol. 1989 Jul 15;38 (14) :2375-81.|[2]Hellberg MR, et al. The hydrolysis of the prostaglandin analog prodrug bimatoprost to 17-phenyl-trinor PGF2alpha by human and rabbit ocular tissue. J Ocul Pharmacol Ther. 2003 Apr;19 (2) :97-103.

Room temperature

http://file.medchemexpress.com/batch_PDF/HY-W746807/

Reference compound1

No Development Reported