Biotine-lipopolysaccharide, van E.coli O111:B4

Biotin-Lipopolysaccharide, from E.coli O111:B4 (Biotin-LPS, from Escherichia coli (O111:B4) ) is a biotin-conjugated Lipopolysaccharide (LPS) that can be coupled with streptavidin protein. Biotin-Lipopolysaccharide, from E.coli O111:B4 can be used to identify Lipopolysaccharide ligands. Lipopolysaccharides, from E. coli O111:B4 (LPS, from Escherichia coli (O111:B4) ) are endotoxins and TLR4 activators extracted from Escherichia coli (E. coli O111:B4) and are classified as S (smooth) type LPS. Lipopolysaccharides, from E. coli O111:B4 possess the typical three-part structure: O-antigen, R3-type core oligosaccharide, and lipid A. Lipopolysaccharides, from E. coli O111:B4 activate TLR-4 in immune cells and can cause significant gastric diseases. Lipopolysaccharides, from E. coli O111:B4 can also induce M1-type polarization in mouse macrophages[1][2][3][4][5]. It is recommended to prepare a solution with concentration ≥2 mg/mL. Vortex thoroughly for more than 10 minutes. Due to the adsorption characteristics of LPS, silanized container or low adsorption centrifuge tubes should be used for aliquoting and storage, and mix thoroughly before use.

Biotin-LPS, from Escherichia coli (O111:B4)

12352200

Biochemical Assay Reagents

Others

Inflammation/Immunology

[Lipopolysaccharide(Biotinylated),fromE.coliO111:B4]

[1]Kabanov DS, et al. Structural analysis of lipopolysaccharides from Gram-negative bacteria. Biochemistry (Mosc) . 2010 Apr;75 (4) :383-404.|[2]Ying Liu, et al. Podocyte-Released Migrasomes in Urine Serve as an Indicator for Early Podocyte Injury. Kidney Dis (Basel) . 2020 Nov;6 (6) :422-433.|[3]Heinrichs DE, et al. Molecular basis for structural diversity in the core regions of the lipopolysaccharides of Escherichia coli and Salmonella enterica. Mol Microbiol. 1998 Oct;30 (2) :221-32.|[4]Cai KC, et al. Age and sex differences in immune response following LPS treatment in mice. Brain Behav Immun. 2016 Nov;58:327-337.|[5]Vogel DY, et al. Human macrophage polarization in vitro: maturation and activation methods compared. Immunobiology. 2014 Sep;219 (9) :695-703

Blue Ice

-20°C, 3 years (Powder)

http://file.medchemexpress.com/batch_PDF/HY-D1056F/Biotin-Lipopolysaccharide-from-E-coli-O111-B4-SDS-MedChemExpress.pdf

Biochemical Assay Reagents

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