Biotinyleerd humaan HLA-DPA1*01:03&HLA-DPB1*04:01&CLIP (PVSKMRMATPLLMQA) Complex Proteïne (Monomer, MALS geverifieerd)
Gecertificeerd

Biotinyleerd humaan HLA-DPA1*01:03&HLA-DPB1*04:01&CLIP (PVSKMRMATPLLMQA) Complex Proteïne (Monomer, MALS geverifieerd)

Catalog #: HLP-H82Ea-25ug
Maat: 25 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100
Technische Documentatie

Technische Specificaties

Background

HLA-DP is a isotype of MHC Class II responsible for presenting foreign antigens to the immune system's helper T-cells. The CLIP peptide, derived from the invariant chain, occupies the peptide-binding groove of the newly synthesized HLA-DP molecule to prevent it from loading irrelevant peptides inside the cell.

Description

HLA-DP is a isotype of MHC Class II responsible for presenting foreign antigens to the immune system's helper T-cells. The CLIP peptide, derived from the invariant chain, occupies the peptide-binding groove of the newly synthesized HLA-DP molecule to prevent it from loading irrelevant peptides inside the cell.

Specifications

Biotinylated Human HLA-DPA1*01:03&HLA-DPB1*04:01&CLIP (PVSKMRMATPLLMQA) Complex Protein is produced by co-expression of HLA-DPA1*01:03 and HLA-DPB1*04:01 loaded with CLIP peptide. This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag (Avitag™) . The protein has a calculated MW of 29.5 kDa and 29.2 kDa. The protein migrates as 38-41 kDa and 33-36 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.

Expression Region

Ala 29 - Glu 222 (HLA-DPA1*01:03) & Arg 30 - Lys 225 (HLA-DPB1*04:01) & PVSKMRMATPLLMQA

Target

HLA-DPA1*0103 & HLA-DPB1*0401 & CLIP (PVSKMRMATPLLMQA)

Conjugation

Biotin-labeled

Tag

C-10xHis & C-Avi

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Purity

90%

Format

Powder

Buffer

PBS, pH7.4

Molecular Weight

29.5 kDa and 29.2 kDa

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

25ug*1

Host or Source

HEK293

Species

Human

Protein ID

P20036 (HLA-DPA1*01:03) & P04440 (HLA-DPB1*04:01) & PVSKMRMATPLLMQA

Preservative

Trehalose

Beschrijving

HLA-DP is a isotype of MHC Class II responsible for presenting foreign antigens to the immune system's helper T-cells. The CLIP peptide, derived from the invari

Specificaties

ProductnaamBiotinyleerd humaan HLA-DPA1*01:03&HLA-DPB1*04:01&CLIP (PVSKMRMATPLLMQA) Complex Proteïne (Monomer, MALS geverifieerd)
Categorie
Beschikbare grootte25 µg
CatalogusnummerHLP-H82Ea-25ug