Biotinyleerd Mouse Monoclonal Antibody to Pembrolizumab (Clone: 10E12C6)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresectable or metastatic melanoma. Pembrolizumab binds to the human cell surface receptor PD-1 (Programmed Cell Death Protein 1) and blocks its interaction with PD-L1, resulting in the activation of T-cell-mediated immune responses against tumor cells. Anti-Pembrolizumab Antibody (10E12C6) [BIOTIN], mAb, Mouse is produced from a hybridoma resulting from the fusion of SP2/0 myeloma and B-lymphocytes obtained from a mouse immunized with Pembrolizumab.
• Mouse
Pembrolizumab
• Monoclonal
10E12C6
ELISA
Protein A chromatography
Purified
0.5 mg/mL, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.
ELISA detection: 0.01-0.1 μg/mL ELISA blocking: 10-50 μg/mL
Mouse IgG1, Kappa
Biotin
Beschrijving
Pembrolizumab (Keytruda) is a humanized monoclonal antibody that is approved by the U.S. Food and Drug Administration for the treatment of patients with unresec
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