BIRC3 Antilichaam

This gene encodes a member of the IAP family of proteins that inhibit apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. The encoded protein inhibits apoptosis induced by serum deprivation but does not affect apoptosis resulting from exposure to menadione, a potent inducer of free radicals. It contains 3 baculovirus IAP repeats and a ring finger domain. Transcript variants encoding the same isoform have been identified.

330

Q13489

Human

Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human BIRC3 (NP_001156.1) .

Unconjugated

Primary Antibodies

Apoptosis, Cancer, Cell Cycle, Immunology

Affinity purification

U-937

Batch dependent

PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

None

Blue Ice

Store at -20˚ C. Avoid freeze / thaw cycles.

Observed: 68kDa

IgG

BIRC3

Baculoviral IAP repeat containing 3

Homo sapiens

BIRC3, TNFR2-TRAF signaling complex protein, RNF49, MIHC, MALT2, HIAP1, HAIP1, c-IAP2, CIAP2, baculoviral IAP repeat-containing protein 3, baculoviral IAP repeat-containing 3, apoptosis inhibitor 2, API2, AIP1, IAP1

WB, IF

Liquid