BIRC5 Mouse Monoclonal Antibody [Kloon ID: LBI2D9]

This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors yet low in adult tissues. Antisense transcripts are involved in the regulation of this gene's expression. At least four transcript variants encoding distinct isoforms have been found for this gene, but the full-length natures of only three of them have been determined.

Carrier-free (BSA/glycerol-free) BIRC5/Survivin mouse monoclonal antibody, clone LBI2D9

API4; EPR-1

Homo sapiens baculoviral IAP repeat containing 5 (BIRC5), transcript variant 1, mRNA.

332

O15392

Unconjugated

Colorectal cancer, Pathways in cancer

Colorectal cancer, Pathways in cancer

WB 1:2000, IF 1:100, FLOW 1:100

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Druggable Genome, Stem cell - Pluripotency

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

BIRC5

https://www.ncbi.nlm.nih.gov/gene/?term=332

https://www.uniprot.org/uniprot/O15392