BIRCH (Ab 142) Antilichaam

GATA1 encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

2623

P15976

NP_002040.1

Human, Mouse, Rat

GATA1 (Ab-142) antibody was raised against a peptide sequence around aa.140~144 (R-L-S-P-D) derived from Human GATA1.

Unconjugated

Primary Antibodies

Other

Antibodies were purified by affinity-chromatography using epitope-specific peptide.

1 mg/mL

Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

None

Blue Ice

Store antibody at -20˚ C for up to one year.

43 kDa

This antibody detects endogenous level of total GATA1 protein.

Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100, Immunofluorescence: 1:100~1:200

GATA1

GATA binding protein 1 (globin transcription factor 1)

Homo sapiens

Zon LI, et al. (1990) Proc Natl Acad. Sci USA. 87: 668-672. Trainor C D, et al. (1990) Nature. 343: 92-96. Nichols K E, et al. (2000) Nat Genet. 24: 266-270. Freson K, et al. (2001) Blood. 98: 85-92. Mehaffey M G, et al. (2001) Blood. 98: 2681-2688.

GF1, GF-1, NFE1, XLTT, ERYF1, NF-E1, XLANP, XLTDA, GATA-1, PLC1, GAT1, GATA1

WB, IHC, IF

4503925

Liquid