Bis-PEG2-amine-Thalidomide (hydrochloride)
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
Bis-PEG2-amine-Thalidomide hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Bis-PEG2-amine-Thalidomide hydrochloride can be linked to a target protein ligand via a linker to form a PROTAC.
Ligands for E3 Ligase
PROTAC
Cancer-programmed cell death
Cancer
NCCOCCOCCOC1=C2C(N(C(C2=CC=C1)=O)C3CCC(N(C3=O)CCOCCOCCN)=O)=O.Cl
C25H37ClN4O9
573.04
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-W1130371/
Reference compound1
No Development Reported
Cereblon
Beschrijving
Bis-PEG2-amine-Thalidomide hydrochloride is an E3 ubiquitin ligase cereblon (CRBN) ligand used to recruit the cereblon protein. Bis-PEG2-amine-Thalidomide hydro
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