
BIW-8962
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BIW-8962 is a humanized anti-ganglioside GM2 antibody. BIW-8962 exhibits ADCC/CDC activity against multiple myeloma cells. BIW-8962 demonstrates potent anti-tumor activity in mouse xenograft models. BIW-8962 is indicated for research in myeloma and other cancers[1][2].
12352100
Apoptosis
Apoptosis
Cancer-programmed cell death
Cancer
[1]Toshihiko Ishii, et al. A Humanized Anti-Ganglioside GM2 Antibody, BIW-8962, Exhibits ADCC/CDC Activity against Multiple Myeloma Cells and Potent Anti- Tumor Activity in Mouse Xenograft Models.. Blood 2008; 112 (11) : 1718. |[2]Yamada T, et al. Genetically engineered humanized anti-ganglioside GM2 antibody against multiple organ metastasis produced by GM2-expressing small-cell lung cancer cells. Cancer Sci. 2011 Dec;102 (12) :2157-63.
Room temperature
http://file.medchemexpress.com/batch_PDF/HY-P991639/
Inhibitory Antibodies
No Development Reported
Beschrijving
BIW-8962 is a humanized anti-ganglioside GM2 antibody. BIW-8962 exhibits ADCC/CDC activity against multiple myeloma cells. BIW-8962 demonstrates potent anti-tum
Specificaties
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