BIX-01294 trihydrochloride
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
1392399-03-9
C13117-10mg
Histone Methyltransferase
Epigenetics
CN1CCCN (CC1) C2=NC3=CC (=C (C=C3C (=N2) NC4CCN (CC4) CC5=CC=CC=C5) OC) OC.Cl.Cl.Cl
C28H38N6O2.3HCl
BIX-01294 trihydrochloride is an inhibitor of G9a histone methyltransferase with IC50 of 2.7 μM in a cell-free assay, reduces H3K9me2 of bulk histones, also weakly inhibits GLP (primarily H3K9me3), no significant activity observed at other histone methyltransferases. BIX01294 induces autophagy. BIX01294 also inhibits H3K36 methylation by oncoproteins NSD1, NSD2 and NSD3.
2 years -80 in solvent
Beschrijving
BIX-01294 trihydrochloride Beschikbaar in 10 mg. Wordt geleverd met droogijs. Bestel eenvoudig online met snelle levering.
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