BLNK Mouse Monoclonal Antibody [Kloon ID: LBI2B2]
Gecertificeerd

BLNK Mouse Monoclonal Antibody [Kloon ID: LBI2B2]

Catalog #: AMM18417VCF
Maat: 100 µg

Kwaliteit

ISO Gecertificeerd

Levering

24-48 uur

Prijs -1%
Login voor prijs
BTW niet inbegrepen
Gratis verzending vanaf €100

Technische Specificaties

Background

This gene encodes a cytoplasmic linker or adaptor protein that plays a critical role in B cell development. This protein bridges B cell receptor-associated kinase activation with downstream signaling pathways, thereby affecting various biological functions. The phosphorylation of five tyrosine residues is necessary for this protein to nucleate distinct signaling effectors following B cell receptor activation. Mutations in this gene cause hypoglobulinemia and absent B cells, a disease in which the pro- to pre-B-cell transition is developmentally blocked. Deficiency in this protein has also been shown in some cases of pre-B acute lymphoblastic leukemia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2012]

Overview

Carrier-free (BSA/glycerol-free) BLNK mouse monoclonal antibody, clone LBI2B2

Synonyms

AGM4; BASH; bca; BLNK-S; LY57; SLP-65; SLP65

Gene Name

Homo sapiens B cell linker (BLNK), transcript variant 1, mRNA.

Gene ID

29760

UniProt

Q8WV28

Conjugation

Unconjugated

Related Pathways

B cell receptor signaling pathway, Primary immunodeficiency

Field of Research

B cell receptor signaling pathway, Primary immunodeficiency

Dilution

WB 1:2000

Form

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Buffer

Lyophilized powder (original buffer 1X PBS, pH 7.3, 8% trehalose)

Function

Druggable Genome

Storage Conditions

Stable for 1 year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and opening the cap. Aliquot will be stable at 4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Symbol

BLNK

Gene ID URL

https://www.ncbi.nlm.nih.gov/gene/?term=29760

Uniprot URL

https://www.uniprot.org/uniprot/Q8WV28

Beschrijving

BLNK Mouse Monoclonal Antibody [Kloon ID: LBI2B2] Beschikbaar in 100 µg. Bestel eenvoudig online met snelle levering.

Specificaties

ProductnaamBLNK Mouse Monoclonal Antibody [Kloon ID: LBI2B2]
Categorie
Beschikbare grootte100 µg
CatalogusnummerAMM18417VCF