BMP-4 Recombinant eiwit

Bone morphogenetic proteins (BMPs) constitute a subfamily within the TGF-β superfamily of structurally related signaling proteins. Members of this superfamily are widely distributed throughout the body and are involved in diverse physiological processes during both pre- and postnatal life. Like BMP-7, BMP-4 is involved in the development and maintenance of bone and cartilage. Reduced expression of BMP-4 is associated with a number of bone diseases, including the heritable disorder Fibrodysplasia Ossificans Progressiva. ProSci’s E.coli derived BMP-4 is a fully active homodimeric protein consisting of two 106 amino acid subunits which correspond to amino acids 303-408 of the full length BMP-4 precursor.

652

P12644

NP_001193.2

Recombinant Proteins

E. coli

Cancer, Growth Factors, Signal Transduction, Stem Cell, Other

Greater than 98% by SDS-PAGE gel and HPLC analyses.

Room Temp

The lyophilized BMP-4 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted BMP-4 stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing BMP-4 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

Bone morphogenetic protein 4

Homo sapiens

ZYME, BMP2B, OFC11, BMP2B1, MCOPS6, DVR4, Bone morphogenetic protein 4, Bone morphogenetic protein 2B, BMP-4

Human

157276593

Lyophilized