BMP15 Antilichaam

BMP15 Antibody: BMP15, or GDF9B is a member of the bone morphogenetic protein family which is part of the transforming growth factor-beta superfamily that are involved in embryonic development and adult tissue homeostasis. BMP15 is expressed exclusively in the oocyte. It is an oocyte-specific growth/differentiation factor that may be involved in oocyte maturation and follicular development. Defects in BMP15 are the cause of ovarian dysgenesis type 2. BMP15 could be used as an oogenesis marker to track human amniotic fluid stem cells differentiation into the oocyte-like cells.

9210

O95972

NP_005439

Human, Mouse

Unconjugated

Primary Antibodies

Stem Cell

BMP15 Antibody is affinity chromatography purified via peptide column.

Cat. No. 1313 - Human Testis Tissue Lysate

1 mg/mL

Predicted species reactivity based on immunogen sequence: Bovine: (75%), Sheep: (75%)

BMP15 Antibody is supplied in PBS containing 0.02% sodium azide.

None

Blue Ice

BMP15 antibody can be stored at 4˚ C for three months and -20˚ C, stable for up to one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.

IgG

It is closely related to GDF9.

BMP15

Cat. No. 17-201 - 3T3/BALB Cell Slide

Bone morphogenetic protein 15

Homo sapiens

Massagué J. The transforming growth factor-beta family. Ann. Rev. Cell. Biol. 1990; 6:597-641

Aaltonen J, Laitinen MP, Vuojolainen K, et al. Human growth differentiation factor 9 (GDF-9) and its novel homolog GDF-9B are expressed in oocytes during early foliculogenesis. J. Clin. Endocrinol. Metab. 1999; 84:2744-50.

Laitinen M, Vuojolainen K, Jaatinen R, et al. A novel growth differentiation factor-9 (GDF-9) related factor is coexpressed with GDF-9 in mouse oocytes during folliculogenesis. Mech. Dev. 1998; 78:135-40.

Galloway SM, Gregan SM, Wilson T et al. Bmp15 mutations and ovarian function. Mol. Cell Endocrinol. 2002; 191:15-8.

BMP15 Antibody: ODG2, POF4, GDF9B, Bone morphogenetic protein 15, BMP-15

ELISA, WB, ICC, IF

257743454

Liquid