
BMS-986156
Kwaliteit
ISO Gecertificeerd
Levering
24-48 uur
Technische Specificaties
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody agonist corticosteroid-induced tumor necrosis factor receptor-related protein (GITR) . BMS-986156 binds to GITR and promotes activation of T effector cells and inactivates T regulatory cells. BMS-986156 is indicated for use in advanced solid tumor studies[1].
12352203
TNF Receptor
Apoptosis
Cancer-programmed cell death
Cancer
97.11
[BMS-986156]
(145.97 kDa)
[1]Siu, Lillian L., et al. Preliminary results of a phase I/IIa study of BMS-986156 (glucocorticoid-induced tumor necrosis factor receptor–related gene [GITR] agonist), alone and in combination with nivolumab in pts with advanced solid tumors (2017) :104-104.
Dry Ice
-80°C
http://file.medchemexpress.com/batch_PDF/HY-P991178/BMS-986156-SDS-MedChemExpress.pdf
Inhibitory Antibodies
Phase 2
Beschrijving
BMS-986156 is a fully humanized IgG1 agonist monoclonal antibody agonist corticosteroid-induced tumor necrosis factor receptor-related protein (GITR) . BMS-9861
Specificaties
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